To avoid the dependency on the quality of the supply, you should tie the reference not to PIC's supply but to a voltage derived from the supply of the flex sensors. If the supply of the flex sensor is greater than the PIC's supply, you can drop the voltage down using a voltage divider. If the flex sensor's supply isn't stable/clean, at least Vref will vary with it at the same time. That is one purpose of having a separate Vref. Another is to tie Vref to a precision voltage reference.